Modelling evolution of virulence in populations with a distributed parasite load
نویسندگان
چکیده
منابع مشابه
Evolution of Parasite Virulence
Diseases causedbyparasite or pathogen infections impair normal functioning in organisms. These impairments can include very diverse symptoms leading to the organism’s morbidity and mortality. Studies of the evolution of the virulence of infectious diseases strive to understand the expression of these symptoms as the result of the evolutionary process. This approach is primarily focused on the e...
متن کاملMechanisms of pathogenesis and the evolution of parasite virulence.
When studying how much a parasite harms its host, evolutionary biologists turn to the evolutionary theory of virulence. That theory has been successful in predicting how parasite virulence evolves in response to changes in epidemiological conditions of parasite transmission or to perturbations induced by drug treatments. The evolutionary theory of virulence is, however, nearly silent about the ...
متن کاملHost mortality, predation and the evolution of parasite virulence
Karen Choo, Paul D. Williams and Troy Day* Department of Zoology, University of Toronto, 25 Harbord Street, Toronto, Ontario, M5S 3G5, Canada Departments of Mathematics and Biology, Jeffery Hall, Queen’s University, Kingston, Ontario, K7L 3N6, Canada *Correspondence: E-mail: [email protected] Abstract One of the most accepted views in the theoretical literature on virulence evolution is that...
متن کاملWithin-host parasite cooperation and the evolution of virulence.
Infections by multiple genotypes are common in nature and are known to select for higher levels of virulence for some parasites. When parasites produce public goods (PGs) within the host, such co-infections have been predicted to select for lower levels of virulence. However, this prediction is based on simplifying assumptions regarding epidemiological feedbacks on the multiplicity of infection...
متن کاملEvolution of parasite virulence against qualitative or quantitative host resistance.
We analysed the effects of two different modes of host resistance on the evolution of parasite virulence. Hosts can either adopt an all-or-nothing qualitative response (i.e. resistant hosts cannot be infected) or a quantitative form of resistance (i.e. which reduces the within-host growth rate of the parasite). We show that the mode of host resistance greatly affects the evolutionary outcome. S...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Mathematical Biology
سال: 2019
ISSN: 0303-6812,1432-1416
DOI: 10.1007/s00285-019-01351-6